Pyrenochaeta unguis-hominis is a dematiaceous filamentous fungus which causes infection to human. It is probably inhabit from soil and previous studies showed that it can be colonized at the nails that have been predisposed to disease and infection (1). The healthy nail will become discoloured after being infected (2). For P. unguis-hominis UM256, it has been isolated from the skin scrapping of the patient. Besides, P. unguis-hominis UM256 is also resistance to most of the antifungal agent, including ketonazole, fluconazole, intraconazole, posaconazole and caspofungin.


The colonies of P. unguis-hominis are slow growing, dark green to dark grey colour and have whitish border from front. They appeared flat, from woolly to cottony. From reverse, the colonies are in dark brown colour. Septate hyphae, pycnidia, conidia, and conidiophores are observed through the light microscopy. The pycnidia of the fungus are solitary, in globose or flask-shaped, and are in brown colour to black. The pycnidia consist of several short and spare septate setae and phoma-like conidiogeneous cells. Conidiophores are branched, septate and hyaline and emerging from the inner surface of the pycnidial wall. The conida of P. unguis-hominis usually are hyaline, single, smooth wall, and short cylindrical.



1. Punithalingam E. Infection of the finger-nail by Pyrenochaeta unguis-hominis.British Journal of Dermatology.1980; 103:91.
2. Punithalingam E. Pyrenochaeta unguis-hominis on human toe-nails. Transactions of the British Mycological Society.1975; 64:539.


Pyrenochaeta unguis-hominis UM 256

  • Description
  • Morphological
  • References
  • Taxonomic Classification
  • Assembly
  • Gene Models
  • Gene Annotations
  • External Links
  • Sequencing Stats
  • Download Data (Contigs)
  • Download Data (Amino Acids)
  • Download Data (Nucleotides)
  • GBrowse Link

    Taxonomic Classification

    Kingdom: Fungi
    Phylum: Ascomycota
    Class: Dothideomycetes
    Order: Pleosporales
    Family: Cucurbitariaceae
    Genus: Pyrenochaeta
    Species: Pyrenochaeta unguis-hominis


    Strain Details

    Stock Number1197
    Morphological IdentityPhoma sp.
    Molecular IdentityPyrenochaeta unguis-hominis
    Isolation LocationSkin scraping
    Collection Date3/5/2011
    Isolation CountryMalaysia



    Assembly size(bp): 35,484,281
    Number of contigs: 286
    Number of contigs (>=200bp): 286
    Total contigs size(bp): 35,449,666
    Contigs N50(bp): 457,153
    Contigs GC content(%): 50.4
    Number of scaffolds (>=1000bp): 254
    Total scaffolds size(bp): 35,484,281
    Scaffolds N50(bp): 481,751
    Scaffolds GC content(%): 50.35

    Gene Models

    Number of predicted genes (>=99bp): 12,545
    Average gene length: 1,517
    Average number of exons per gene: 2.76
    rRNAs: 33
    tRNAs: 121

    Gene Annotations

    KEGG : 1337
    EC : 2555
    GO : 7616
    KOG : 6813
    PFAM :
    Interpro : 9223
    CAZyme : 808
    CAZyme Unique : 725
    Secondary Metabolite : 21
    Peptidase : 192
    Peptidase Unique : 187
    Virulence Factor : 454

  • NCBI Taxonomy
  • Catalogue of Life
  • Organism Platform Read type Library size(bp) Number of reads Read length(bp) Total read size(bp) Estimated genome size(Mbp) Sequencing coverage(X)
    Pyrenochaeta Roche 454 GS FLX+ Single End - 1,225,229 817 1,001,317,541 39.4 25
    Pyrenochaeta Roche 454 GS Junior Pair End 3,000 199,554 394 78,541,005 39.4 2